There are both unknown and known genetic factors like SNPs which are responsible for male pattern baldness. â€œThe researches show that there are many genes which affect androgenetic alopecia but variations in one gene, that is AR, have been recognized. The AR gene gives instructions for making protein, which is called androgen receptorâ€ (â€œAndrogenetic Alopeciaâ€, par. 6). With the help of AR the body is able to respond to dhydrotestosterone and other androgens. The deviation in androgen receptor (AR) gene is responsible for reducing the age of hairs of men. This is the stage when men start losing hair and become bald. There was a long established notion that male pattern baldness was caused by a single gene that was passed on by mother on the X chromosome. It was also believed that the hair loss would occur in a typical manner and women were less prone to this type of pattern baldness. AR gene exists in the X chromosome. It is commonly understood that baldness is normally inherited from mother to son. A man inherits X chromosome from his mother. He has one X chromosome. â€œA man having baldness-promoting version of the AR is believed that he has received it from his mother. But his mother receives one X chromosome from her mother and one from her father. It makes sense that baldness could have come from manâ€™s maternal grandfatherâ€ (â€œMale Pattern Baldnessâ€, par. 7).
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