The use of microalgae as biomass for biofuel production in biorefineries is feasible because they could be grown in optimal conditions and increase exponentially over a short period of time (Oncel, 2013). The rapid growth favors mass production of biofuels because of continuous input of raw materials (Mata, Martins & Caetano, 2010). The problem that scientists could solve in the future is designing a microalgae biorefinery that could produce large amounts of biofuels at a low cost. Upcoming biotechnology firms have taken an initiative to solve this problem by adopting biotechnology approaches in cultivation of microalgae for biorefineries (Ziolkowska & Simon, 2013). The open cultivation of microalgae could expose them to their predators, and this could result in big losses (Harun & Danquah, 2011). The processes involved in microalgae biorefineries are very expensive and, in most cases, do not make economic sense (Singh & Gu, 2010). Nevertheless, the adoption of microalgae for large-scale production of biofuels in biorefineries has many opportunities in the future (Lam & Lee, 2012; Pienkos & Darzins, 2009).
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